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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241777a86451a9e953e07f40c5bf754ab509c415cef5d27c13a1ca9da7c1ddcf' 
  AND token = '/vkiYv7UZXptjKIPC0NbLDSBOp+cRJkjaRyZVQFxpCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}