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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09cf89addb5503f577a8293d07ab1ed2bcc135ee03c20e6bbb95fdca224caec1' 
  AND token = 'QDG3yPSEAURr/c4e3ZQ2RsxTYzORWmE4dJYNtUhsPD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}