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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730d7a473c160c2f2cc36e7a5421bba0403c4a0dfd468d7030d7ae77d00b85e5' 
  AND token = '48cCkdBMb0DXTvH6mfVS3olPQs8s40CkUX09xjeuta4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}