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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5845fbcccd94b0d9473d38c9ba33b4cded3a3a9fe4de13ccbd8451033c9014' 
  AND token = 'nEux5hoY7YOZBZ49o//RsrV2om2vuwofY5FF0r8kyY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}