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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150f7fc9f78a0200bb362fa70c2c311c0e0b38e20249c6bc0c6fcae42ab664b8' 
  AND token = 'IPM+BwQCkHWYwVKzg5X+K0mFxiNRcenk7t9dHdOQN50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}