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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd07e4e23defe0293be60adb59d20546d8e3a9657c642f45bd1feaf36eacbcead' 
  AND token = 'zNUzyJNJKkgCw0fC8FKMX/IaeunC0jp8NXPwmOPYGC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}