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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93e3c297c6fcd04f9910c43d2a4ad1c612e139670160673d1ee2c84153470310' 
  AND token = '9yEHrQEdSjJgpVQqmUqnoC+47kMx4JJ5VOHGvN4DAHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}