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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7708535c4f1ca8c17a61776a2a6dbd986e07173119e5d36f432670cde73d820f' 
  AND token = '72UFaS6g0hOMxBGvUylkzEVgAQH+0fsak6DoETLC6fU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}