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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f821920f06b0062c23d0efd9413369b03a4b9bc440313522ab12da29a02ddf' 
  AND token = 'ymbqr4BNN2m7T1dS3SvNP6zGo2fzD8lVQ3nnqic+nzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}