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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067b727f7cca1584fb56312be25cfa8de6037c5f679b8f413927f8b7cbc0e3be' 
  AND token = 'NWYH1kRRZTDC9AAt0C13rGCjV+ebs3GTAr2qUXLOLmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}