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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1545376f97c344645e623c2d8128c2d780e668d7ce77553e1f74495e49fd0aac' 
  AND token = 'rP6wzTXERdLvF2Snaz9SiK1DCvqE+y+y5aRMhyhi8O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}