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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3c76b91dfbb57b3d3ee8956adb0b48f539f82f57ab6cbbcedd850c310ce6d4' 
  AND token = '7z54D0NrILcQRV1QeB/+PazXpZvPrF2rmDBwvj/BUUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}