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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56e60dea0fa0d7d17d9eacc63c75ac9f30845ec782c259fa2099b4eeddca4b71' 
  AND token = 'D4Nb0GYPIKb3MzNT7clYbTwK6dZHajDzGvLMZwPLAFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}