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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b327c7fa6a06b77f3747fc1803f709ea928a0c1cac299625ee902f4a2efc491' 
  AND token = 'CLw9q7//2M9QVZXqh4t7fz3NWoGylU4PRY1W4GPz7is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}