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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b8490cea3ac94a09cd9da05a9d9181edbf309bc04c8032681da4acb939d8d84' 
  AND token = 'fiu0Qk2iDAmFyq0qekaVpp9a/4mih4tiay1uUoDy1ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}