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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48b22d1b96746302df09bfc5502018eae8b4d8c411dc0d94ddd45633b7c1730' 
  AND token = '11b2CFAreK6Cd4yrxqhUY7pqG5IRs4NDe3p/9r6ekds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}