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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253a82ed6f1f7dce22f6e52d1ea28c0df936e8c322950a3ca04084ea6acd587f' 
  AND token = '5Np7Jwnj38NMfIfxqPh7VDUXj4knSfzstaHZrsQWzqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}