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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293c0d93e7959a795d8ea06e35f7f4f14050ee4623b564756042de4ce86a9894' 
  AND token = 'VwKhZ+gDMNAKqEl3PyZHo8MHVtNSvh89O01CZ6GMdKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}