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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5f76ebef864bd606d43a57d0a38f6f50ee8f499c94620f149e97c481550856' 
  AND token = 'i9YF2m+cCITS3Tner37IYZAnpmEkUtbqy5TQ6QDMp4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}