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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8010149d619776816def6f9784246817f814ca603953f63801d84ab34512ef39' 
  AND token = 'hdY7D4PHMLmsqrcBDjs7e06E0y4RH/9DmeALkMJhn9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}