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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c61712d1ba7af05d263f8a595d0e97b3b69d9edf2da9f09ca0139559928b7f66' 
  AND token = 'qSFqEkKBTGTlPuOrlMwMpqiPN83/VaNfvsX7Weh2vQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}