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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bcf3ed688a4e34395dca6cafd42db2aeaa3b7578902541cb91bdcb51783bf74' 
  AND token = 'esjjs5mi0E7ONvie/YPU/0irsEfhzcmWxDGn7SeoGyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}