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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '355322563de0e5d26185c8c43498be9e37aa85d59b6a1dd1afad51b64b49c7d8' 
  AND token = 'GVrIqDfH9n2TStuHHFk1GqyK9LZb4WRzgvmmyK7Ab9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}