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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa75e4323886391188446f50ab019203830edbfc69390b4c0645e6023751a57' 
  AND token = 'A+rSm5o2bG5fW8ClBHgwmj8FfaxIT+5kCYjiaF4SC6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}