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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572c421e0f9dfecab8e8a4db784f8ea01ff5d012944b1e5301bd99afda40213b' 
  AND token = 'NfXO41ODoHotJzgQ79egZ1pgomyYRhU5xWEnlw67gqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}