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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7575f5d74d62e08e932bc812115e5347f02c209ec364dee5244a102f68b2cab5' 
  AND token = 'ozb3dXOuShcvRIJxKWb2hRwYwWeXoVnpo032zYUWJlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}