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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95423771321a74ecbb643828174de6840745c8ef456888fa8e264829a54c1b60' 
  AND token = 'lE2OzJccpp2xpfmUvQzcJhiTD/p4Q0wwXl1xOJCfIIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}