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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da503b4b43eedb30de9138cf581b29c15438c238d3ee3c156f9d6bf2e7dfb604' 
  AND token = 'HNSwaEQ1TOZjksAy7NXtgELWPPGgEF+pPw524vgNgvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}