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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3972daf88c82d439e3595b25142d7864c2e6457c318f61bce1e686dae392746' 
  AND token = 'GYfZhJ520uq2Ukb/9h2Gy/oty1tQyiUT0GdN2CgbwP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}