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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c784a9b21fc2317a46ef5091cbc129a2867f76eed12a91d1fa86d39cd9e62dd' 
  AND token = 'y6RuMDuTSVzzDFrvVgScaHxoO01xtKlpqiHKpMk08AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}