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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1566b6949bd943648ee03353b3690947ae3f4309a9ff7b4f53f8a7047970d7b2' 
  AND token = 'Rk0wFyExOE4GuRIbJKKa1NRdgdfT3vj7urjeHZPuXmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}