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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86a8234fd1c895d129239d93a929240d8234adf5915248ad04a9b8f0d164611' 
  AND token = 'a8Ln2w7Hx0j4dSPux4+6NZwXwd1GigrpDET+6TBrzNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}