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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c3b2e0f2b3d969f927b68189d3574fb3b287ddd14f7ea5c44c39a2c23eca18' 
  AND token = 'Orb7FZP8moUv50ptrWskFeojpRhQgiyhbsbxIOCQWaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}