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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901a15d07fa2de1ceb771f3dd0d2a2d5625c405485eb616251bb08e9d9a0d3f7' 
  AND token = '5QBu85ZyYE2MjvrLUD/gNUdW8VPF1FNHWfdPOxsp74w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}