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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e088aef72d44aae53c1caf408e89704ebaa24d15feec0190c58048d78cca33' 
  AND token = '9ZnwhcV+4e3UvhoUcb6+OXgpTBrsB0TzB6GYqGPqWgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}