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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3a9d26d15e4f2254294fb2ee95c29fd2616f19e67694bafb7932c62333624e' 
  AND token = 'qV1k5dlUlsbwH4PCEHJ2BQnW1qXfBfpmxPfHcHDZTts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}