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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e9404295a2573e4a9a2bc3ea6655a7429759db50a82b83d5a57e1a136b3c53' 
  AND token = 't/Trmg31sk+k53mz5FkhyiUvY+8Cz3mgDeymJ0UDn7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}