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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d48bc08e44e28e550ccc52b72b87a07d76c4e05399d8feb058c1a07f927566f' 
  AND token = 'jIttpXKPEPVQhurcpny2pU/I8P6KsfCg54GCDsk0Yk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}