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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225f832b0f5d2e3039ba343cd6d957cc1f02fddf113a01e144b2e656667e315a' 
  AND token = 'oXl3fad57zQLgWtH74vOCg3ILXjdlrAOdbgwUJXpX78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}