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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c33ce25369e706624ec99ae9f6ccbd994e9365b9861daa43ec9c5f571090ea6' 
  AND token = 'Q+4tAb8ahHi6hfKfzUMS/NM7QhNIGL1dWoRPRNgGffE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}