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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '640d26543882088036b6dc412ae7c077098c09342ea76fdd9e2476fb3a3fcbb8' 
  AND token = 'Z3Rg3ujeWB7cGw1Wr5eSR9Byjkxbxx/P3tz8JvD6/0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}