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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287cae8454ca8c14f1da1e5c0072f20251cd236de84577b041a5124834a4636c' 
  AND token = 'YtrzTr3wQzdL+r5/eJIaEqs7yUkyvSGmblOh27ZXcPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}