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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c001b22be0c3bd4552e4db5fee3c5c2dc68ed9d99a9017d2ea51961725f1e012' 
  AND token = 'xTWWPLXCaCQGg2CN5ogMQqBIZqrhE7CsK6EuIi25TbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}