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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08ecf923f2541aeed058cc6849369b6c87b695ecf3c37c979642af3844b658f' 
  AND token = 'vgbW0DX0z1RFRTtFXIaYtpUCKJK+WDbMWyAfzfM4EOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}