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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35b9928527fcf9a0f0e08823b0ec0d04b44881de7c65579561dc9f10b33f16c' 
  AND token = '+sPLU6/OmJbAlhdc1kbfyMJsZpyGjpN8ci2hnKToiAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}