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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f722c20dad606dbed0b326f524d23a080253fff2ae3dbd0be4ca746a4fe3e85' 
  AND token = 'P/7CqyTSz6+y8ukAkGkjvR1GDR6U+g64YVg157Fxzvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}