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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ff31049941af277aee5000c002f611068732268bb2621e4e5e0a1df1001fe8' 
  AND token = '2Mm6F9JnXm4VM3aCN7XLksTpApX7hfNK5ysejc++4gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}