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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d3927cd4ed3da8dd5e56d5d3d56b7bc3e15edbe8f407e9abebed3770269272' 
  AND token = 'qicbPgu+aoOwnzg7Ncivijs4J3/dYma+7uBNh80/Xm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}