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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea6b3784d04c8329069dc10e4cc19045da7dd6daa8280d6e7849778bc6edab38' 
  AND token = 'iVkLp/61VpP6lkRhg9+MwpFjzEgyRSIBwAthXuGXQwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}