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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d78e178b83922af3a78f76c7945e8567192e2b4e34ba1c335dc0b8b5a1258d' 
  AND token = 'QsJoj2IveM74t5rW5oeufLeLVxCiT1IE56IuknQTKfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}